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Lack of Human Studies Most research has been conducted in animal models
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Its an investigational compound
Also, the male KO mice had an increased CYP1A2 (Part of the P450 enzyme family that are responsible for a large part of detoxification), however this wouldnt really explain the differences seen in Figure 2 (side-note: Ok, this last part was extremely geeky and I try to make this as mainstream as possible
What the evidence actually shows for BPC-157 is a consistent preclinical record across tendon, ligament, and muscle injury models, a 2025 systematic review confirming preclinical support (Vasireddi et al.), and a small human retrospective study showing 91.6% patient improvement in chronic knee pain cases
