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This superior efficacy helped it achieve global sales of ~US$16.4bn in 2024 (Mounjaro ~US$11.5bn and Zepbound ~US$4.9bn), rivalling semaglutide and completely overshadowing the sales of historical GLP-1s, such as exenatide, liraglutide and dulaglutide [FIGURE TWO]
Participants were mostly women (65%), average age 55 years, with mean BMI 39typical of real-world obesity profiles
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It is exclusively prepared for patients with clinical needs that cannot be met by commercially available alternatives and is not for resale, bulk distribution, or office use
We used to think there was only one kind of type-2 diabetic
Why These Limitations Matter for Interpretation Taken together, the limitations mean GHRP-2 should be understood as a scientifically important and well-characterized research compound genuinely valuable for what it taught endocrinology about the ghrelin/GHS-R1a system, and genuinely useful as a diagnostic probe but not as a validated therapy
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