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Chronic obstructive pulmonary disease in never-smokers: risk factors, pathogenesis, and implications for prevention and treatment

This dose was chosen based on a previous dose-escalation study and subsequent work demonstrating its efficacy to drive weight loss in a short period of time 8

Monogenic disease genes and hypertension-associated variants identified in GWAS provide important insights into the pathophysiology of hypertension and are potential targets for the development of novel antihypertensive agents

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66-79, 10.1016/j.lfs.2017.08.006