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3-HK is a pro-oxidative, pro-inflammatory and neurotoxic metabolite, and its toxic mechanism is mainly related to oxidative stress [23]

Both intermittent dosing schedules (injections on specific days) and continuous daily administration showed benefits, suggesting some flexibility in protocol design

e-h , HCC-1806 cells were grown without or with MK-571 (15 M) in control (208 M cystine