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The science on L-carnitine is a bit more encouraging than on chitosan
Two early trials (ADJUNCT ONE and TWO) showed increased risks of symptomatic hypoglycemia and hyperglycemia with ketosis associated with liraglutide 8,9
While safety within the phase 3 program is sufficient for marketing authorization (although the risk of cardiovascular events should not exceed a hazard ratio of 1.8 according to a guidance document that was released by the FDA at that time), it is the post-marketing phase in which rare adverse events and any other potential safety risks are identified or resolved
Adv Ther (2020) 37(10):442745
Clean handling, careful storage, and tidy reconstitution keep the process stable
At the same time, GLP-1 RAs cause the body to release more insulin in response to food intake, which results in sugar moving into cells to provide energy, thus lowering the amount of glucose in the blood stream (known as blood sugars or blood glucose)
