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Ceruloplasmin oxidation, a feature of parkinsons disease CSF, inhibits ferroxidase activity and promotes cellular iron retention
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A number of small, poorly controlled studies have reported that either acute (dose given one hour before exercise bout) or short-term (two to three weeks) supplementation with L-carnitine (2 to 4 g/day) supported energy production, cardiorespiratory fitness, and endurance capacity during physical exercise (reviewed in 129)
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They are caused by the physical act of injection plus local immune response to the injected substance
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