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Here's the TL;DR on vitamin timing: while there is no official medical advice dictating that you should take vitamin supplements at a specific time of day to improve their efficiency, there is quite a lot of research showing that avoiding some vitamin supplements at particular times (or more accurately, with particular meals) can improve absorption, or that taking some vitamins alongside food can reduce the risk of adverse side effects

It also helps prevent the formation of new fat and may improve bone density

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Auxotrophic Actinobacillus pleurpneumoniae grows in multispecies biofilms without the [PMID: 27349384] Laboratory literature summary: Auxotrophic Actinobacillus pleurpneumoniae grows in multispecies biofilms without the need for nicotinamide-adenine dinucleotide (NAD)

Because B12 is so closely linked to energy production and normal bodily function, it has become a common supplement in wellness and weight-loss settings