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Key highlights: Demonstrated sustained improvements across symptomatic, clinical, endoscopic, histologic, and quality-of-life endpoints Benefits seen even in ~27% of patients who had failed prior biologics or advanced therapies Long-term safety profile consistent with prior findings no new safety signals Among patients continuing from blinded maintenance to the open-label extension, 12% reported serious adverse events, 7% discontinued due to adverse events Approved for UC and Crohns disease in 44 countries These results (from the LUCENT-3 extension) were shared at UEG Week 2025 in Berlin and mark a significant milestone in the pursuit of durable, steroid-free remission for IBD patients
The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40
The issue of weight management has become one of the most popular in healthcare practices in the UK, especially with the ever-increasing rate of obesity
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Eso no parece mucho, ya que se estima que 854,000 estadounidenses sin diabetes usaron medicamentos GLP-1 para perder peso en 2022, pero los medicamentos son costosos, y pueden costar cerca de $1,000 o ms al mes, encontraron los investigadores
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