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Published human trials report mild gastrointestinal discomfort in 814% of participants and transient headache in 57%, with symptoms typically resolving within 23 weeks
Eussen SJ, de Groot LC, Clarke R, Schneede J, Ueland PM, Hoefnagels WH, et al: Oral cyanocobalamin supplementation in older people with vitamin B12 deficiency: a dose-finding trial
Clinical trials conducted in the early 2000s showed modest results, and the compound failed to demonstrate sufficient efficacy to support regulatory approval as a weight-loss medicine
& Oben, J
The idea of over-firing due to extra receptors is speculative
04 How long does it take to feel more energy with these treatments
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