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Lower levels of IGF-1 and growth hormone in older adults have been linked with (5, 14): increased fat mass increased cardiovascular risk decreased muscle mass and strength lower cognitive function lower bone density limited joint mobility Several of these traits are seen in frail older adults

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Common visual characteristics include: Uneven shape Ragged or blurred edges Multiple colors within one lesion Enlargement over time Raised or thickened areas New skin spots appearing in adulthood Surface changes such as crusting or bleeding A melanoma lesion may look dramatically different from the rest of your moles

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