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Chen, J.-J

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IGF-1 induces insulin-like effects on glucose uptake, and chronic elevations may lead to reduced insulin sensitivity. LeRoith, Trends in Endocrinology & Metabolism IGF-1 DES Side Effects 1

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Put simply: for every 4,500 people treated with a GLP-1 agent over five years, roughly one additional case of NAION MAY, I repeat MAY occur compared to a matched diabetic population not on the drug