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The lysine-proline-valine sequence binds to MC1R on immune cells including macrophages, mast cells, and T-lymphocytes, triggering downstream inhibition of nuclear factor kappa B (NF-B)the transcription factor responsible for upregulating pro-inflammatory cytokines including TNF-, IL-6, and IL-1

menciona que casi no hay reportes de reacciones adversas y sugiere que podra ser una herramienta prometedora para lesiones hipovasculares)pubmed.ncbi.nlm.nih.govpubmed.ncbi.nlm.nih.gov

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"Delta sleep inducing peptide (DSIP) stimulates the release of LH but not FSH via a hypothalamic site of action in the rat"