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The side effects of semaglutide, particularly the gastrointestinal ones, occur directly because of how the drug works

10.1016/j.celrep.2017.05.077 64 ServilloL.D'OnofrioN.GiovaneA.CasaleR.CautelaD.CastaldoD.et al (2018)

All interventions were compared with current use of SGLT2is (20% of the total population) and GLP-1 RAs (5% of the total population)

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