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Common reasons for digestive upset include: High Dosages: Taking more than 1,000mg to 2,000mg at once can overwhelm the guts ability to transport the nutrient

Journal of Acquired Immunodeficiency Syndromes, 53 (3), 311-322

They're also coloured purple so you can clearly differentiate between them and other types of syringes

Roesel RA, Hommes FA, Samper L: Pyroglutamic aciduria (5-oxoprolinuria) without glutathione synthetase deficiency and with decreased pyroglutamate hydrolase activity

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The effects of serotonin in immune cells