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Notably, the DNA damage response protein MRE11 activates the cGASSTING pathway, thereby driving necroptosis mediated by the ZBP1RIPK3MLKL axis [57]
It should also be noted that IL-4 promotes the differentiation of Th0 cells into Th2 cells, exacerbates the inflammatory response, and leads to IgE production in the absence of an allergen
No therapeutic claims are made or implied
Siddiqui et al., 2021)
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