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J Alzheimers Dis
More recently, the SUMMIT trial demonstrated that tirzepatide reduced the composite risk of cardiovascular death or worsening heart failure by 38% (HR = 0.62, 95% CI: 0.410.95) in patients with heart failure with preserved ejection fraction (HFpEF) and a BMI 30 kg/m 2 , 32% of whom also had type 2 diabetes
These are normal immune responses and typically resolve within 2448 hours
In addition, while short and medium term safety profiles from clinical trials are reassuring, long term cardiovascular, pancreatic, and endocrine safety data are still evolving
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Metallomics 2015
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