This reaction has two consequences studied in the literature: it consumes S-adenosyl methionine, the cells principal methyl donor, and it removes nicotinamide from the salvage pathway that regenerates NAD+
[1] It is investigated for its potential role in nitric oxide pathway modulation, growth factor signaling, and extracellular matrix remodeling
How to prevent vitamin B12 deficiency Vitamin B12 deficiency due to diet is rare in the U.S
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Dosing doesn't translate into humans
The before and after result is real, but the timeline is specific to the tissue type and the severity of the condition being treated