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AOD-9604, despite a safety database spanning six trials and around 900 participants, saw its early positive efficacy signal fail to replicate in its largest confirmatory trial meaning its safety data is well established
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"Tesofensine and weight loss Authors' reply." Lancet
Early human trials in people with obesity found that daily AOD9604 was well tolerated and had a safety profile similar to placebo, with no major effects on glucose metabolism or IGF1, though weightloss results were modest and inconsistent
Skipping refrigeration: Reconstituted solution should stay cold
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