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doi.org/10.2174/1381612824666180712110447 Bock-Marquette, I., et al

Relationship of glutathione depletion and inhibition of glutathione-S-transferase [PMID: 3731136] Laboratory literature summary: Relationship of glutathione depletion and inhibition of glutathione-S-transferase activity to the antimitotic properties of estramustine

This interaction increases cell surface ATP levels, which then activates P2X4 purinergic receptors