The mice were randomly divided into four groups (each containing at least five mice): a natural aging group, a natural aging + FOXO4-DRI group, a D-Gal group, and a D-Gal + FOXO4-DRI group
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They have considerable potential for clinical applications, such as treating bacterial infections, tumors, and neuromuscular diseases
Small research studies and anecdotal clinical reports suggest that some people tolerate DSIP without major side effects, but standardized long-term safety studies do not exist
Food and Drug Administration (FDA) for approval on 18 December 2025, with a review decision expected in late 2026
However, the larger surface area makes high-concentration body treatment expensive and impractical