In another study using a model of high fat diet-induced obesity, insulin secretion was improved and prevented extensive peri-insulitis after 11 months of vildagliptin treatment
Combination of exercise and GLP-1 receptor agonist treatment reduces severity of metabolic syndrome, abdominal obesity, and inflammation: a randomized controlled trial
Semaglutide delays 4hour gastric emptying in women with polycystic ovary syndrome and obesity
Additionally, the hormones target the appetite control centers in the brain which, combined with the slower gastric emptying, reduce appetite to help you lose weight
Any cortisol improvement is secondary to improved metabolic health and reduced inflammation
Because there is no cure, patients must balance symptom control against the burden of side effects