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The hypothalamus produces thyrotropin-releasing hormone (TRH), which stimulates the pituitary gland to secrete thyroid-stimulating hormone (TSH)
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heterodimeric pyruvate dehydrogenase (E1p 30copies) (thiamine diphosphate (ThDPdependant), homodimeric dihydrolipoyl transacetylase (E2p12 copies) and dihydrolipoamide dehydrogenase dimer (E3) (FAD containing) residing in the inner mitochondrial membrane [4](Fig
