Doyle ME, Egan JM (2007) Mechanisms of action of glucagon-like peptide 1 in the pancreas
Giamberardino MA, Dragani L, Valente R, Di Lisa F, Saggini R, Vecchiet L
Singal, Ju Dong Yang, Karn Wijarnpreecha Alimentary Pharmacology & Therapeutics .2025
Potential Side Effects and Drug Interactions Berberine is generally considered well-tolerated in the short term, but like any bioactive compound, it can cause adverse effects and interact with medications
Second Nature is an all-in-one service: it prescribes Mounjaro or Wegovy, delivers the medication, and provides dietitian-led coaching alongside a structured behaviour change programme
However, the effects on insulin sensitivity over long-term use are less well understood