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B.AkpoghelieP
K.QiC.LiuX.MaJ.RenJ
Journal of Biological Chemistry, 287(7), 4552-4561
General longevity
[68] [70] [71] Earlier studies found a wide range of inhibitory potencies of valproate against HDACs, ranging from low micromolar to millimolar concentrations, but subsequent work with improved methodology has supported greater inhibitory potencies, with IC 50 values in the range of 36 to 219 M for the class I HDACs
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