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Multi-dose preserved formulations get longer in-use windows because preservatives like benzyl alcohol suppress microbial growth
In monotherapy clinical trials of 50 to 200 mg/day for migraine prophylaxis, the following GU effects occurred more frequently with topiramate than placebo: urinary tract infection (2% to 4% vs
Oliver Sum-Ping, MD, a Clinical Associate Professor of Psychiatry and Sleep Medicine at Stanford Medicine who wasnt affiliated with the research told Healthline, The results suggest substantial potential for the role of these medications for at least mitigating OSA. The SURMOUNT-OSA trial was a multi-center, randomized, double-blind, placebo-controlled trial conducted with 469 patients, all of whom had OSA