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For context, the toxic dose is estimated at roughly 22,500 mg, compared to a typical weekly dose of about 6 mg
[12] They should be stored at controlled room temperature, typically around 20C to 25C (68F to 77F), and kept in a clean, dry place
A second cohort of mice including WT, RAMP1 KO, RAMP3 KO, and RAMP1/3 KO genotypes confirmed that both RAMP1 and RAMP3 are individually essential for a full cagrilintide-induced neuronal activation response