These services offer multidisciplinary support and, where clinically indicated, access to pharmacological treatments, in line with NICE obesity guidance (NICE CG189 and quality standard QS127, alongside relevant technology appraisals)
For GLP-1 RAs, semaglutide was notably associated with a significant risk of biliary tract disorders (n = 188) and infectious biliary disorders (n = 196)
Fat droplet formation decreased, and the cells accumulated less fat even when exposed to conditions that normally promote fat storage
These drugs can lead to significant weight loss, around 10% of body weight within six months, but may also cause side effects
Be aware that these factors have been linked to an increase in androgenize
If you are on both metformin and semaglutide or metformin and tirzepatide , pay extra attention to magnesium and B12 levels