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d , Photomicrographs of cFos immunoreactivity (cFos-ir) in coronal NTS sections from GLP-1R-Cre x PPG-YFP mice bilaterally injected in nodose ganglia with dye (Control) or AAV9-DIO-hM3Dq-mCherry (hM3Dq) and administered saline or CNO (photomicrographs representative of independent experiments from 3/3 animals)
The increased nausea and vomiting aligns with known adverse effects of GLP-1 receptor agonists and supports the outcome detection approach