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It also matters because dehydration from vomiting or diarrhea is easier to manage when you are awake and can sip fluids consistently
Update 15 October: This article was updated to reflect that the Select Trial is funded by Ozempic's manufacturer Novo Nordisk.
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This timing allows any stimulatory effects from the medication to dissipate before evening
Most users see initial improvements within 7-14 days, with continued progress throughout the full protocol
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