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Nanodroplets can become more highly supersaturated, thus reaching higher solute concentration compared to bulk solution, which makes it difficult for models to predict hygroscopicity

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Remien CH, Adler FR, Waddoups L, Box TD, Sussman NL: Mathematical modeling of liver injury and dysfunction after acetaminophen overdose: early discrimination between survival and death

Larger proteins generally excluded though transcytosis possible for specific molecules

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