When administered by licensed medical professionals, vitamin injections are considered safe for most individuals
This helps them learn how to administer the injections and watch for how their body reacts
However, the largest Phase IIb trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading to development termination in 2007
If you are uncomfortable with self-injecting, you can find a local clinic that will be happy to administer them for a small fee
Vitamin B12 is included in the metabolic processes in the body including proteins, carbohydrates, and fats
In proof-of-concept studies, NNMT inhibitors (NNMTis) have demonstrated promise as potential treatments for obesity and obesity-related metabolic comorbidities (e.g., T2D, fatty liver) 8,9,13