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Vighi G, Marcucci F, Sensi L, Di Cara G, Frati F
GSH is also involved in the neutralization of lipid aldehydes (4-HNE, MDA) generated by mitochondrial lipid peroxidation
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Future studies should prioritize brain tissue biopsies, obtained from epilepsy surgery, to map the molecular drivers of ferroptosis and launch phase I/II trials of repurposed iron chelators, such as deferiprone, in drug-resistant cohorts
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