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The NTS itself contains GLP-1 producing neurons which signal to decrease food-based reward in the mesolimbic VTA and NAc, which in turn impact memory and emotional processing in the hippocampus and amygdala [40]
Finalmente, algunos estudios de casos clnicos y series cortas sugieren sus beneficios tambin en pacientes con ERC estadio 5D, aunque debe recordarse que esta indicacin no est incluida en la ficha tcnica de los arGLP-1114,115
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clinician review
406 Kim et al
It is more likely that increased HR results from a direct GLP-1 receptor-mediated effect on the endogenous sinoatrial pacemaker node of the heart, as GLP-1 receptors are expressed in the human heart in myocytes in the sinoatrial node [33]
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