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GH plays a role in several processes relevant to body composition, including: Metabolism and fat utilization: GH is involved in the breakdown and utilization of stored fat for energy
Tirzepatide was associated with an increased thyroid cancer risk (reporting odds ratio [ROR] = 2.09, 95% CI: 1.512.89), though its risk was lower compared to other GLP-1 receptor agonists such as liraglutide (ROR = 15.59) and semaglutide (ROR = 7.61)
More infrequent, rare or serious side effects have also been reported, including low blood sugar, lung aspiration, thyroid cancer and gallstones
The more accurate conclusion is that they may indirectly increase the risk of nutritional shortfalls by reducing appetite, total food intake and dietary variety
People taking the highest dose lost an average of 28.7% of their body weight over 68 weeks
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