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Phentermine is believed to work in various ways, as it has central nervous system (CNS) stimulant effects and helps reduce feelings of hunger
Mechanistically they do not overlap (GLP-1 agonists work through appetite and gastric emptying, this works on adipocyte lipogenesis and NAD+), and the mouse data specifically showed fat loss without reduced food intake, so they are not redundant
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bile acid intermediates)
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