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Management of fatigue in patients taking GLP-1 receptor agonists begins with thorough assessment to identify contributing factors and exclude serious underlying conditions

Rectal bleeding causes include: Hemorrhoids Anal Fissures Anal Cancer Colon Cancer Ulcerative Colitis/Crohns Disease Solitary Rectal Ulcer (ulcer in the rectum) Diverticulosis (a bulging pouch) Proctitis (inflammation of the rectum) Ischemic colitis (a colon inflammation) Infectious Colitis (inflammation of the colon) Colon Cancer Colorectal and anal cancers are more serious causes of rectal bleeding

Over-the-counter anti-nausea remedies should be discussed with your PlexusDx provider before use, as some interact with semaglutide's mechanism

If you want a quick overview video, watch this short explanation here: GLP-1 medication overview

This is uncommon but twitching that lasts weeks, worsens, or affects more than the eyelid deserves a proper assessment rather than reassurance from an article