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iLISI was calculated using the first 20 principal components before Harmony correction and the first 20 Harmony-corrected dimensions after integration, with dataset identity used as the batch label

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Vasile Valeriu Lupu, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

It shields skin cells from damage while simultaneously supporting the cellular processes that maintain hydration, promote collagen synthesis, and contribute to overall skin vitality

The area under the curve was 0.782 (95 % confidence interval: 0.7180.845)

In the absence of coenzyme B12, tetrahydrofolate cannot be regenerated from its inactive storage form, 5-methyltetrahydrofolate, and a functional folate deficiency occurs