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Retrieved from Brotto, L., Atallah, S., Johnson-Agbakwu, C., et al
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This sounds revolutionary, but it has received a mixed reception among clinicians, with many citing concerns that once-monthly dosing may paradoxically worsen patient compliance (patients may simply forget to take the medication, as once-monthly administration may not be frequent enough to build adherence behaviours) and slow dose titration
For couples with male-factor infertility related to obesity and metabolic health, this may be one useful piece of a broader fertility plan
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That said, the women in the placebo groups also showed meaningful improvement, suggesting that there was a noticeable placebo effect that boosted desire as well
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