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Here is some advice on talking to your doctor about starting a GLP-1, a guide to losing weight sans drugs, and an essay about ending generational weight shaming
Indeed, in clinical practice, metformin demonstrated a variety of beneficial effects on menstrual disorder, anovulation, androgen excess, insulin resistance, and cardiovascular risk, whereas its weight loss effect is often inconsistent and transient [21, 22]
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Why GLP-1 Dosing Starts Low GLP-1 dosing typically starts low to prevent tolerance issues and the often-talked-about side effects that affect "digestion, appetite signaling and gut motility," says New York endocrinologist and obesity specialist Rocio Salas-Whalen, MD
Several studies point to a protective role of GLP-1RAs on retinal pigment epithelium (RPE) cells, which form the blood-retinal barrier and are vulnerable to inflammation [83, 84]
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