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For example, in this study, tirzepatide led to an average weight loss of 20.2% compared to 13.7% with semaglutide

Fertility changes: Weight loss can lead to more regular ovulation, which may increase the chances of becoming pregnant

They work through different pathways and can complement each other for blood sugar control and weight loss

Walsh, D

This is particularly relevant to GLP-1 medications, which not only regulate appetite but also act on areas of the brain involved in reward and motivation

Genetic data also informs whether you may benefit from compounded tirzepatide ($289/mo injection, $349/mo oral), which activates both GLP-1 and GIP receptors and may produce different thermoregulatory effects than semaglutide alone