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Long-chain acylcarnitines activate cell stress and myokine release in C2C12 myotubes: calcium-dependent and -independent effects

Preserving it maintains a higher calorie burn at rest, which directly supports long-term weight maintenance after the medication is discontinued

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PMID: 26903002, PMCID: PMC4802449, DOI: 10.1161/jaha.115.002157

In addition, semaglutide works in a glucose-dependent way