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A extenso e a variabilidade nas respostas dos grupos placebos tm sido a maior dificuldade dos estudos que avaliam os efeitos da suplementao sobre a capacidade fsica dos indivduos

Participants provided stool samples, completed diet surveys, and answered online surveys about their experiences with the supplements

Burton GW, Ingold KU

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2013 Apr 24;309(16):1696-703

Large population studies show that adults with lower carotenoid consumption tend to report shorter sleep duration, suggesting that antioxidant status may influence healthy sleep patterns.34 A smaller randomized trial tested 12mg of astaxanthin daily for eight weeks and found improvements in several sleep parameters, along with reduced perceived stress compared to placebo.4 The authors proposed that astaxanthins antioxidant and neuroprotective activity including its ability to cross the bloodbrain barrier could help stabilize oxidative stress in brain regions involved in regulating sleep and mood