What Research Shows (Up to 12 Weeks): Chronic toxicity : None documented (studies up to 12 weeks) Organ damage : None detected in histopathological examination Carcinogenic effects : None observed (though dedicated cancer studies haven't been done) Reproductive toxicity : None found in limited fertility studies What We Don't Know: 1
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25 In SURMOUNT-OSA, tirzepatide treatment in patients with moderate-to-severe obstructive sleep apnea and obesity reduced the apnea-hypopnea index, body weight and hypoxic burden, among additional beneficial effects
If you take opioids/opiates right after stopping naltrexone you may be more sensitive to them (and require lower doses) - which poses a risk of overdose