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This may lead to enhanced binding of inhibitors to other proteins
Structural docking studies show that Cagrilintides hydrophobic residues interact favorably with the transmembrane domains of the CTR, enhancing receptor activation stability
CrossRef Computational approaches to predicting treatment response to obesity using neuroimaging Leonard Kozarzewski, Lukas Maurer, Anja Mhler, Joachim Spranger, Martin Weygandt Reviews in Endocrine and Metabolic Disorders.2022
Experiments with inhibitors of different cell uptake pathways indicate that internalisation of peptides takes place through involvement of clathrin-coated vesicles
1 Steno Diabetes Center Copenhagen, Herlev, Denmark, 2 Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark, 3 Zealand University Hospital, Kge, Denmark, 4 Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark, 5 Clinical Metabolic Physiology, Gentofte Hospital, Hellerup, Denmark
Nutrition Metabolism, 13, 16
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