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Department of Medicine, Weill Cornell Medical Center, New York, New York (Yu)
Alterations in the volume of distribution and clearance resulting from other mechanisms of action (eg, reduced fat mass, changes in cytochrome P450 activity, and glomerular filtration rate) are key factors in determining pharmacokinetics
Real world experience will help clarify best protocols
2022 Mar 30;11(7)
A doctor may recommend further tests to see if there is another reason for the change in weight
As an initial trial examining switching to oral therapy for maintenance of weight reduction, and in the absence of a widely agreed upon definition or calculation to assess maintenance of weight reduction, several endpoints, including additional sensitivity analyses, were evaluated in this trial regarding maintenance and overall change
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