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Excess nicotinamide is eliminated partly through a methylation pathway, meaning it consumes methyl donors in the process of excretion
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It is the most bioavailable form of B12, and also the most active, working mostly in our brains, nervous system, and liver (Lindstrand, 1964)
Reference: Cox, H., Miller, G., & Eichner, D
What is the difference between TB-500 and BPC-157 dosage
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