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The N-terminal methionine oxidizes, creating methionine sulfoxide that alters binding kinetics
Its a natural hormone your gut makes after you eat
As granulomas mature, they develop fibrous walls and experience a significant decrease in the number of vessels penetrating the structure, which hampers the penetration of anti-TB drugs into the necrotic and hypoxic areas of the granuloma, where M.tb persists [98, 99]
& Canales, B
Researchers increasingly focus on neuropeptides connected to stress management and nervous-system regulation pathways
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