demonstrated that in dendritic cells (DCs), LPS-induced glycolysis is repurposed to replenish citrate, an intermediate metabolite in the TCA cycle that is depleted for the de novo synthesis of fatty acids ( 2 ( de novo lipogenesis is important for phagocytosis as it requires ongoing lipid synthesis in the ER for membrane expansion, such that Ms can surround and capture targeted pathogens for internalization ( de novo lipogenesis, an anabolic process that is NADPH-dependent, in regulating the inflammatory response of myeloid cells
doi: 10.1139/y71-047 9 CassoniP.GhC.MarroccoT.TarabraE.AlliaE.CatapanoF.et al
Specifically, nanoliposomes have gained attention as a drug delivery system that has the potential to deliver drugs to the specific target sites of the brain after passing the BBB effectively, using particular pathways 22,23,24
By supporting collagen production, glutathione may contribute to skin radiance
The distinctive characteristics of cells undergoing ferroptosis include a series of morphological abnormalities of mitochondria, such as organelle shrinkage, condensed organelle membrane, and lessened cristae
Originally isolated from human gastric juice, this 15-amino acid compound has been studied in preclinical animal models across multiple physiological systems.*1,9,10
