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Randomized clinical trial: macrogol/PEG 3350 plus electrolytes for treatment of patients with constipation associated with irritable bowel syndrome

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CrossRef The impact of primary tumor location in patients with metastatic colorectal cancer: a Korean Cancer Study Group CO12-04 study Jae Ho Byun, Joong Bae Ahn, Sun Young Kim, Jung Hun Kang, Dae Young Zang, Seok Yun Kang, Myoung Joo Kang, Byoung Yong Shim, Sun Kyung Baek, Bong-Seog Kim, Kyung Hee Lee, Soon Il Lee, Sang-Hee Cho, Byeong Seok Sohn, Samyong Kim, In Gyu Hwang, Eun Mi Nam, B The Korean Journal of Internal Medicine.2019

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Introduction Diabetes, a serious chronic disease, is growing worldwide and is now one of the top ten leading causes of death worldwide ( SCs, as the main glial cells in the peripheral nervous system, possess regenerative properties of interest and have important roles in the nervous system in coordinating the gradual formation of peripheral nerves, ensuring neuronal survival, axonal support and myelination, and promoting neurodegeneration and regeneration ( Programmed cell death (PCD) is an active death process (e.g., apoptosis, autophagy, pyroptosis, ferroptosis, and necroptosis) that occurs after a cell receives a certain stimulus or signal in order to maintain the homeostasis of the internal environment ( SCs are an important link in the pathogenesis of DPN: the role of axons SCs encapsulate all axons in peripheral nerves and maintain the long-term functional integrity of axons ( 2+ homeostasis plays an important role in axon function and integrity ( 2+ to enter axons, leading to abnormal axonal mitochondrial function and the onset of apoptosis (34)