Benefits and possible side effects Potential benefits Clinically meaningful weight loss for many patients Improvements in blood sugar, cholesterol and blood pressure Reduced cravings and improved control around food Common side effects Most side effects occur during dose increases and often settle with time: Nausea Heartburn or reflux Constipation or diarrhoea Reduced appetite or early fullness GLP-1 medicines and HRT: why review matters If you take HRT, especially oral progesterone , it is essential that your clinician knows before starting a GLP-1 medicine
Ozempic (diabetes) accounted for most of these fills, but Wegovy (approved June 2021 for obesity) has been growing faster
Early Morning Reality Check (4-6 AM) Before you even think about food, your bodys stress hormones can mess with your blood sugar control even when youre on semaglutide
Andreu, A., Jimenez, A., Vidal, J., et al
While Reddit, TikTok and X users have raved about their results, medical providers are more skeptical due to a lack of safety data and a lack of oversight into its murky supply chain
If digestion is your main issue, layering adequate fiber and fluids first, then considering a probiotic, is a sensible sequence